Gene Expression Profiles in Chronic Idiopathic (Spontaneous) Urticaria
نویسندگان
چکیده
منابع مشابه
Gene expression profiles in chronic idiopathic (spontaneous) urticaria
BACKGROUND The pathophysiology of chronic idiopathic (spontaneous) urticaria (CIU) is poorly understood. OBJECTIVE We hypothesized that a study of gene expression in active lesions from patients with CIU would uncover unexpected associations. METHODS We enrolled eight patients with CIU and six healthy controls, and obtained 4 mm punch biopsy specimens of active lesions and unaffected skin o...
متن کاملTemperament and character profiles of patients with chronic idiopathic urticaria
INTRODUCTION Psychosocial factors have been implicated as being important in the onset and/or exacerbation of urticaria. AIM To examine both personality factors of patients with chronic idiopathic urticaria (CIU) and the correlations between illness duration, severity of itching, urticaria activity score (UAS) and temperament-character dimensions. MATERIAL AND METHODS A total number of 70 C...
متن کاملOmalizumab for the treatment of chronic idiopathic or spontaneous urticaria.
BACKGROUND Many patients with chronic idiopathic urticaria (also called chronic spontaneous urticaria) do not have a response to therapy with H-antihistamines, even at high doses. In phase 2 trials, omalizumab, an anti-IgE monoclonal antibody [corrected] that targets IgE and affects mast-cell and basophil function, has shown efficacy in such patients. METHODS In this phase 3, multicenter, ran...
متن کاملChronic idiopathic urticaria treatment.
Chronic idiopathic urticaria (CIU) is a common skin condition that affects 0.1-3 % of people in the USA and Europe and accounts for nearly 75 % of all chronic urticaria cases. Up to 40 % of patients who have chronic urticaria for more than 6 months still have urticarial wheals 10 years later. The therapeutic management should first be oriented towards palliation of symptoms. A 2 % solution of e...
متن کاملEffects of Helicobacter Pylori Eradication on Chronic Idiopathic Urticaria
Background: Chronic idiopathic urticaria is defined as urticaria, which lasts for more than 8 weeks and has no apparent etiology. The aim of this study was to examine the causal role of Helicobacter pylori infection in chronic idiopathic urticaria. Methods: Fifty-six patients with chronic idiopathic urticaria and a negative response to skin prick test for common aeroallergens were selected. The...
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ژورنال
عنوان ژورنال: Allergy & Rhinology
سال: 2015
ISSN: 2152-6567,2152-6567
DOI: 10.2500/ar.2015.6.0124